Journal Articles, Journal content

Reactive oxygen species treatment in the management of wounds

Share this article

Reactive oxygen species treatment in the management of wounds

22 November 2017

<p>Bacterial colonisation and biofilm production with subsequent inflammation and infection is a huge global health problem in wounds especially in diabetes, burn victims, the elderly. In an era of increasing antimicrobial resistance, there are few entirely novel antimicrobial agents in development and antibiotics have limited efficacy in the presence of heavy bacterial bioburden and biofilm. A novel therapy with activity against bacterial load and biofilm is Reactive Oxygen Species (ROS), oxygen radicals, as an antimicrobial mechanism. ROS can be delivered to the site of infection in various formats. ROS is highly antimicrobial against Gram positive and negative bacteria, viruses and fungi. It prevents and breaks down biofilm. These functions make ROS potentially highly suitable for chronic soft tissue inflammation: wounds, ulcers and burns. In addition to its therapeutic role, ROS could play an important part in surgical prophylaxis, infection prevention and antimicrobial stewardship.</p>

Free for all healthcare professionals

Sign up to the Wounds Group journals

By clicking ‘Subscribe’, you are agreeing that the Wounds Group are able to email you periodic newsletters. You may unsubscribe from these at any time. Your info is safe with us and we will never sell or trade your details. For information please review our privacy policy.

Are you a healthcare professional? This website is for healthcare professionals only. To continue, please confirm that you are a healthcare professional below.

We use cookies responsibly to ensure that we give you the best experience on our website. If you continue without changing your browser settings, we’ll assume that you are happy to receive all cookies on this website. Read about how we use cookies.

I am not a healthcare professional.